It eliminates the accumulation of potassium and lipofuchsine. The transfer of potassium and sodium across the membranes is vital for proper cellular communication and can be inhibited by lipofuchsine. Centrophenoxine is very effective in treating various disorders associated with brain damage due to aging, a stroke, drugs or chemicals, including excessive consumption of alcohol. It also provides protection against chemical environment.
Centrophenoxine is composed of two biochemicals: diethylaminoethanol (DMAE) and parachlorophénoxyacétate (PCPA). DMAE is a natural compound found in foods like fish. It is also a metabolite of choline, which occurs naturally in the body of man. The PCPA is a synthetic compound similar to a variety of plant hormones called "auxin."
Both are, amongst others, powerful antioxidants that protect the brain from free radical damage. The PCPA is also an analog of pyroglutamic acid (PCA) , which is naturally present in the brain. The beneficial therapeutic effects of centrophenoxine were observed particularly in cases of cerebral atrophy, brain injury, post apoplectic state (after a stroke), chronic alcoholism or barbiturate poisoning. Clinical studies on patients with symptoms such as confusion, psychosomatic asthenia (extreme weakness), disturbances of memory or concentration Intellectual show significant progress after only a few weeks of treatment. Scientific works published in European literature have reported a marked improvement in symptoms such as fatigue, irritability, confusion or memory loss in geriatric patients treated with centrophenoxine.
In two small pilot studies, patients with tardive dyskinesia, a neurological disorder characterized by abnormal involuntary movements and a variety of mouth, tongue, jaw, neck or extremities, centrophenoxine causes a very substantial reduction in these symptoms in about two-thirds of patients.
Regular intake of centrophenoxine can prevent mental deterioration. It improves memory performance among healthy individuals, as in those with dementia. The body produces choline, but a large part is provided by food. Thus, liver, meat and eggs provide high amounts of choline, but processed foods in our modern diets or vegetarian diets contain little.
A diet too low in choline is incompatible with good health. It should be noted that a number of studies have linked the excess of self-cannibalization neuronal choline during the life of the genesis of Alzheimer's disease. Consumption of foods rich in choline, lecithin dietary supplement Choline, DMAE or centrophenoxine may increase plasma levels of choline up to 30 micromoles and even more with, for results, levels of higher brain choline and acetylcholine. Nutritional supplements such as choline chloride or choline bitartrate choline have low bioavailability and are often destroyed almost 60 percent by bacteria in the gut.
It was shown that prolonged administration of centrophenoxine to healthy aging animal, that it leads to significant reduction of lipofuchsine. In mice, a significant reduction was observed after six weeks. A study on rats showed a decreased age of 25 and 42 percent levels lipofuchsine in different brain regions after eight weeks of treatment. Lipofuchsine decrease and an increase in antioxidant enzymes in the cerebellar cortex were found after six weeks of treatment in rats aged 6, 9 and 12 months.
Life expectancy of animals taking centrophenoxine was much longer than those who did not take it. This is the only study that scientifically proves that taking centrophenoxine prolongs life expectancy of animals. Studies in animals and humans have shown that low levels of lipofuchsine are correlated with healthy cell function while elevated levels of lipofuchsine are synonymous with poor cellular health.
Older animals whose levels were reduced by lipofuchsine centrophenoxine had their memory and learning abilities restored to levels similar to those in young animals. Scientific research has shown that centrophenoxine can reduce the quantities of lipofuchsine in nerve cells, suggesting that its beneficial effects on mental functioning of people with dementia are partly due to this action. Many researchers believe that profits are also generated through improved cellular metabolism.
Food is probably the most important element in the fight against aging. A balanced and varied diet will provide minerals, vitamins, fiber, trace elements, fat acids, which are essential for the activity of your enzymes, enabling the fight against oxidative stress and stimulating the defense systems of your body.